Karlowicze is mentioned in 1554 as a courtyard belonging to the Kiezgajl family, from 1558 to the Vilna chapter. In 1558 in the inventory of the Borodino parish Karlowicze is mentioned as “land ... of that Lithuanian village”, from which they gave ‘three buckets of honey and all other payments’.
In 1588 there were 3 houses in the village, which paid a tax of 3 kapa and 1 grosz Lithuanian.
Since 1795 it was part of the Russian Empire, in Kobryn district, Slonim district, since 1797 Lithuanian, since 1801 Grodno province.
In 1890 the folwark as part of the Zakoziel estate belonged to Kalikst Orzeszko. In 1905 the folwark in Wolowiel parish, Kobryn district, Grodno province had 60 inhabitants.
From 1921 to 1939 it was part of Poland, in Wolowiel commune, Drohiczyn district, Polesie Voivodeship. In 1921 the folwark had 3 courtyards and 31 inhabitants.
From 1939 it was part of the BSSR, in Drohiczyn district, Pinsk region. From 15.01.1940 in Drohiczyn district, from 12.10.1940 in Karolin village council. There were 27 households and 127 inhabitants.
During the Great Patriotic War 3 inhabitants of the village died. Since 1954 it has been part of Brest region. In 1960 the village was in Popina village council with 132 inhabitants, in 1970 — 85 inhabitants, in 1995 — 18 yards and 37 inhabitants.