Osipowicze is mentioned in 1546, in the description of the borders between the Grand Duchy of Lithuania and the Crown of Poland. It was a village in Kobryn district, the property of “Pan Andrei the Doctor”. In 1783 it was included in Holowczyce key, Brest district. In 1791 in Kobryn district, from 1795 in Russian Empire, Kobryn district, Slonim province, from 1797 in Lithuanian, from 1801 in Grodno province. In 1858, the village Osipowicze in Antopol volost, Kobryn district, the center of the village community.

The village of Osowlane was mentioned in 1858, as part of Imienin parish, Kobryn district, Grodno province. There were 13 “souls” (state villagers) in the village, formerly subordinated to the Torokany monastery. Schubert’s map of 1870: In 1905 the village had 285 inhabitants. In 1921-39 it was part of Poland, Imienin commune, Drohiczyn district, Drohiczyn county, Poleskie voivodeship. In 1921 the village had 52 courtyards, 133 inhabitants (all Orthodox). WIG map: From 04.

Orlowicze as a folwark was first mentioned in 1628 and 1698. In 1860 the village and the estate (Horlowicze) in Perkovitska and then Wolowiel volosts, Kobryn district, Grodno province. There were 129 “souls” in the village, they also belonged to the Horlowicze estate, which belonged to Felix Wyslouch (206 “souls”). During the uprising of 1863-64, the estate was used as an ammunition depot for the rebels. After the Orlovic family became the owners of the Rusecky family.